CP-690550 N-Hydroxyl

CAS: 2407039-29-4

Ref. TR-C781820

Product Information

• Name: CP-690550 N-Hydroxyl
• Synonyms: (3R,​4R)​-3-​[(7-​Hydroxy-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​4-​yl)​methylamino]​-​4-​methyl-​β-​oxo-​1-​piperidinepropanenit​rile, 3-((3R,4R)-3-((7-Hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
• CAS: 2407039-29-4

Description

Impurity CP-690550 Impurity
Applications CP-690550 N-Hydroxyl is an impurity of CP-690550 (C781350), a pyrrolo[2,3-d]pyrimidine derivative, as Janus kinase inhibitor for treatment of rheumatoid arthritis.
References Sheiner, L., et al.: Clin. Pharmacol. Ther., 25, 358 (1979); Dayneka, N., et al.: J. Pharmacokin. Biopharm., 21, 457 (1993); Changelian, P., et al.: Science, 302, 875 (2003); Lee, H., et al.: Clin. Pharmacol. Ther., 73, 348 (2003); Hutmacher, M., et al.: J. Clin. Pharmacol., 47, 238 (2007)

• Brand: TRC

Chemical properties

• Molecular weight: 328.369
• Formula: C₁₆H₂₀N₆O₂
• Color/Form: Light Brown to Brown Solid
• InChI: InChI=1S/C16H20N6O2/c1-11-4-7-21(14(23)3-6-17)9-13(11)20(2)15-12-5-8-22(24)16(12)19-10-18-15/h5,8,10-11,13,24H,3-4,7,9H2,1-2H3/t11-,13+/m1/s1
• SMILES: C[C@@H]1CCN(C(=O)CC#N)C[C@@H]1N(C)c1ncnc2c1ccn2O