N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-L-valine Methyl Ester

CAS: 137863-90-2

Ref. TR-C962370

Product Information

• Name: N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-L-valine Methyl Ester
• Synonyms: L-Valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-, methyl ester, <span class="text-smallcaps">L</span>-Valine, N-[(2′-cyano[1,1′-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-, methyl ester, L-valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-, methyl ester, Methyl N-[(2'-cyanobiphenyl-4-yl)methyl]-N-pentanoyl-L-valinate, N-[(2′-Cyano[1,1′-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-<span class="text-smallcaps">L</span>-valine methyl ester, [N-(2-Cyanobiphenyl-4-Yl)Methyl]N-Valery-(L)-Valine Methyl Ester, methyl (2S)-2-[[4-(2-cyanophenyl)phenyl]methyl-pentanoyl-amino]-3-methyl-butanoate, methyl N-valeryl-N-[(2'-cyanobiphenyl-4-yl)methyl]-L-valinate
• CAS: 137863-90-2

Description

Applications N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-L-valine Methyl Ester is an impurity of the drug Valsartan (V095750), which is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 406.52
• Formula: C₂₅H₃₀N₂O₃
• Color/Form: Colourless Oily
• InChI: InChI=1S/C25H30N2O3/c1-5-6-11-23(28)27(24(18(2)3)25(29)30-4)17-19-12-14-20(15-13-19)22-10-8-7-9-21(22)16-26/h7-10,12-15,18,24H,5-6,11,17H2,1-4H3/t24-/m0/s1
• SMILES: CCCCC(=O)N(Cc1ccc(-c2ccccc2C#N)cc1)C(C(=O)OC)C(C)C