6-Cyano-7-nitroquinoxaline-2,3-dione

CAS: 115066-14-3

Ref. TR-C982000

Product Information

• Name: 6-Cyano-7-nitroquinoxaline-2,3-dione
• Synonyms: 7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile, 1,2,3,4-Tetrahydro-7-nitro-2,3-dioxo-6-quinoxalinecarbonitrile, 2,3-Dioxo-7-nitro-1,2,3,4-tetrahydroquinoxaline-6-carbonitrile, 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline, 6-Cyano-7-Nitroquinoxaline-2,3-Dione 2Na, 6-Cyano-7-Nitroquinoxaline-2,3-Dione Disodium, 6-Cyano-7-Nitroquinoxaline-2,3-Dione Disodium Salt, 6-Quinoxalinecarbonitrile, 1,2,3,4-tetrahydro-7-nitro-2,3-dioxo-, 7-Nitro-2,3-Dioxo-2,3-Dihydroquinoxaline-6-Carbonitrile, Cnqx, Cnqx 2Na, Cnqx Disodium, Cnqx Disodium Salt, Disodium 6-Cyano-7-Nitroquinoxaline-2,3-Diolate, Fg 9065

Description

Stability Store Tightly Sealed at RT
Applications A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively.
References Honore, et al. Science, 241, 701 (1988),Haas, H.S., et al.: Int. J. Oncol., 27, 867 (2005), Kobayashi, K., et al.: J. Pharmacol. Sci., 108, 517 (2008), Shabat-Simon, M., et al.: J. Neurosci., 28, 8406 (2008), Cruz, L.A., et al.: J. Med. Chem., 51, 5856 (2008),

• Brand: TRC

Chemical properties

• Molecular weight: 232.15
• Formula: C₉H₄N₄O₄
• Color/Form: Neat
• InChI: InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15)
• SMILES: N#Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1[N+](=O)[O-]