N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide

CAS: 90357-51-0

Ref. TR-C987585

Product Information

• Name: N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
• Synonyms: Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl- (9CI), 2-Methyloxirane-2-carboxylic acid N-(4-cyano-3-trifluoromethylphenyl)amide, Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-, (+/-)-, 1,2-Epoxy-2-Methyl-N-[4-Cyano-3-(Trifluoromethyl)], 1,2-Epoxy-2-Methyl-N[4-Cyano-3(Trifluoromethyl)-Phenyl]Propanamide, 2-Methyl-oxirane-2-carboxylic acid (4-cyano-3-trifluoromethylphenyl)-amide, 2-Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-, 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropioanilide, Carboxamide, N-[4-Cyano-3-(Triflouromethyl)Phenyl]-2-Methyl-2-Oxirane Carboxamide, N-[4-Cyano-3-(Trifluoromethyl)Phenyl]Methacrylamide Epoxide, N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxiranecarboxamide, N-[4-Cyano-3-(trifluoromethyl)phenyl]-methacrylamide exoxide, N-[4-Cyano-3-Trifluoromethy Phenyl]-2-Oxirane Carboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide, Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-, Phenyl]-2-methyl-2-oxirane, n-[4-cyano-3-(triflouromethyl)
• CAS: 90357-51-0

Description

Impurity Bicalutamide Oxirane Impurity / Bicalutamide Epoxide Impurity
Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.
References Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009);

• Brand: TRC

Chemical properties

• Molecular weight: 270.21
• Formula: C₁₂H₉F₃N₂O₂
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C12H9F3N2O2/c1-11(6-19-11)10(18)17-8-3-2-7(5-16)9(4-8)12(13,14)15/h2-4H,6H2,1H3,(H,17,18)
• InChI key: InChIKey=GPGKZPUNVOBAKA-LLVKDONJSA-N
• SMILES: C[C@]1(C(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)CO1