N-Cyano-3-(cyanoamino)-N'-methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-imidamide (Cimetidine Impurity)

CAS: 74886-59-2

Ref. TR-C988275

Product Information

• Name: N-Cyano-3-(cyanoamino)-N'-methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-imidamide (Cimetidine Impurity)
• Synonyms: Cimetidine Imp. H (EP), 1,1'-(Disulphanediyldiethylene)bis(2-cyano-3-methylguanidine), Cimetidine Hydrochloride Impurity H, Cimetidine Impurity H, Cimetidine Impurity H,1,1'-(Disulphanediyldiethylene)bis(2-cyano-3-methylguanidine), Cimetidine Hydrochloride Imp. H (EP)

Description

Impurity Cimetidine EP Impurity H
Applications N-Cyano-3-(cyanoamino)-N'-methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-imidamide (Cimetidine EP Impurity H) is an impurity of Cimetidine (C441650), an H2-receptor antagonist that is used for the treatment and prevention of stress-induced gastroduodenal lesions.
References Burland, W., et al.: Brit. J. Clin. Pharm., 2, 481 (1975); Kauffman, G. & Morton, I.: Gastroenterology, 75, 1099 (1978); Peura, D. & Johnson, L.: Ann. Int. Med., 103, 173 (1985)

• Brand: TRC

Chemical properties

• Molecular weight: 314.43
• Formula: C₁₀H₁₈N₈S₂
• Color/Form: Off-White
• InChI: InChI=1S/C10H18N8S2/c1-13-9(17-7-11)15-3-5-19-20-6-4-16-10(14-2)18-8-12/h3-6H2,1-2H3,(H2,13,15,17)(H2,14,16,18)
• SMILES: CN/C(=N/C#N)NCCSSCCN/C(=N/C#N)NC