Cyproterone

CAS: 2098-66-0

Ref. TR-C989090

Product Information

• Name: Cyproterone
• Synonyms: 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1,2-dihydro-17-hydroxy-, (1beta,2beta)-, 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1beta,2beta-dihydro-17-hydroxy- (8CI), Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1alpha,2alpha-methylene- (7CI), (1beta,2beta)-6-Chloro-1,2-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 1,2alpha-Methylene-6-chloro-6-17alpha-hydroxyprogesterone, 6-Chloro-1,2alpha-methylene-4,6-pregnadien-17alpha-ol-3,20-dione, 6-Chloro-17-hydroxy-1alpha,2alpha-methylenepregna-4,6-diene-3,20-dione, 6-Chloro-6-dehydro-17alpha-hydroxy-1,2alpha-methyleneprogesterone, SH 80881, SH 881, (1R,3aS,3bR,7aR,8aS,8bS,8cS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1R,7aR,8aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1R,7aR,8bS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1β,2β)-6-Chloro-1,2-dihydro-17-hydroxy-3′H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 1,2α-Methylene-6-chloro-⁶-17α-hydroxyprogesterone, 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 6-chloro-1-beta,2-beta-dihydro-17-hydroxy-, 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1,2-dihydro-17-hydroxy-, (1β,2β)-, 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1β,2β-dihydro-17-hydroxy-, 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron, 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron [German], 6-Chloro-1,2α-methylene-4,6-pregnadien-17α-ol-3,20-dione, 6-Chloro-17-hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione, 6-Chloro-6-dehydro-17α-hydroxy-1,2α-methyleneprogesterone, Bay 94-8367, Bay94-8367, Ciproterona, Ciproterona [INN-Spanish], Ciproterone, Ciproterone [DCIT], Cyproteron, Cyproterone [INN:BAN], Cyproteronum, Cyproteronum [INN-Latin], Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1α,2α-methylene-, Sh 80881, Sh 881, Unii-E61Q31Ek2F
• CAS: 2098-66-0

Description

Impurity Cyproterone Acetate EP Impurity F
Applications Cyproterone (Cyproterone Acetate EP Impurity F) is an antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsexuals.
References Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007), Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 374.90
• Formula: C₂₂H₂₇ClO₃
• Color/Form: Off White Solid
• InChI: InChI=1S/C22H27ClO3/c1-11(24)22(26)7-5-14-12-9-18(23)17-10-19(25)13-8-16(13)21(17,3)15(12)4-6-20(14,22)2/h9-10,12-16,26H,4-8H2,1-3H3/t12-,13+,14-,15-,16-,20-,21-,22-/m0/s1
• InChI key: InChIKey=DUSHUSLJJMDGTE-ZJPMUUANSA-N
• SMILES: CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@@]21C