Cynarin Sodium Salt

CAS: 30964-13-7

Ref. TR-C991477

Product Information

• Name: Cynarin Sodium Salt
• Synonyms: (1R,3R,4S,5R)-1,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxycyclohexanecarboxylic acid, (1R,3R,4S,5R)-1,3-Bis{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-4,5-dihydroxycyclohexancarbons?ure, (1R,3R,4S,5R)-1,3-Bis{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-4,5-dihydroxycyclohexanecarboxylic acid, (1R,3R,4S,5R)-1,3-Bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-4,5-dihydroxycyclohexanecarboxylic acid, (1S,2S,3S,4R)-1,4-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-2,3-dihydroxycyclohexanecarboxylic acid, (1S,3R,4R,5R)-1,3-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-4,5-dihydroxycyclohexanecarboxylic acid, (3R,5R)-1-acetyl-3,5-dihydroxycyclohexane-1,4-diyl (2E,2'E)bis[3-(3,4-dihydroxyphenyl)prop-2-enoate], 1,4-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-3,5-dihydroxycyclohexanecarboxylic acid, 1,5-Dicaffeoylquinic Acid, 1,5-Dicaffeylquinic Acid, 1-Carboxy-4,5-dihydroxy-1,3-cyclohexylenebis-(3,4-dihydroxycinnamate), 3,4-Dihydroxycinnamic Acid 1-Carboxy-4,5-dihydroxy-1,3-cyclohexylene Ester, 4-{[3-(3,4-dihydroxyphenyl)acryloyl]oxy}-1-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-3,5-dihydroxycyclohexanecarboxylic acid, Acide (1R,3R,4S,5R)-1,3-bis{[(2E)-3-(3,4-dihydroxyphényl)-2-propènan-1-oyl]oxy}-4,5-dihydroxycyclohexanecarboxylique, Caffeic Acid 1-Carboxy-4,5-dihydroxy-1,3-cyclohexylene Ester, Cinarin, Cinarine, Cinnamic acid, 3,4-dihydroxy-, 1-carboxy-4,5-dihydroxy-1,3-cyclohexylene ester, Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-, Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-, Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxy-, [1R-(1α,3α,4α,5β)]-, Cynarin, Cynarin(1,3-Dicaffeoylquinic Acid), Cynarine, Lynare Scolymusl P.E., [1R-(1a,3a,4a,5b)]-1,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxycyclohexanecarboxylic Acid, cyclohexanecarboxylic acid, 1,3-bis[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-

Description

Stability Hygroscopic
Applications Cynarin Sodium Salt is used on MDR cells in anti-cancer therapy as an inhibitor of P-glycoprotein-mediated transport.
References Angelini, A. et al.: J. Biol. Red. Homeostat. Agents., 26, 495 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 538.433
• Formula: C₂₅H₂₃NaO₁₂
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C25H24O12.Na/c26-15-5-1-13(9-17(15)28)3-7-21(31)36-20-12-25(24(34)35,11-19(30)23(20)33)37-22(32)8-4-14-2-6-16(27)18(29)10-14;/h1-10,19-20,23,26-30,33H,11-12H2,(H,34,35);/q;+1/p-1/b7-3+,8-4+;/t19-,20-,23+,25-;/m1./s1
• InChI key: InChIKey=ICFXYUMXKYMFFI-SXYVKZDHSA-M
• SMILES: O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H]1C[C@@](OC(=O)/C=C/c2ccc(O)c(O)c2)(C(=O)O[Na])C[C@@H](O)[C@@H]1O