Dabigatran Acyl-Beta-D-Glucuronide Trifluoroacetic Acid Salt (80%)
CAS: 1015167-40-4
Ref. TR-D100085
| 1mg | 903.00 € | ||
| 10mg | 6,366.00 € |
Product Information
- N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-ß-alanine ß-D-Glucopyranuronosyl Ester Trifluoroacetic Acid Salt
Stability Unstable in Solution
Applications Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt is a major metabolite of Dabigatran (D100090) in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. NMR analysis confirmed the structures of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers).
References Becker, B., et al.: Biochem. J., 314, 249 (1996), Bailey, M., et al.: Chem. Biol. Interact., 145, 117 (2004), Blech, S., et al.: Drug Metab. Dispos., 2008, 36, 386 (2008),
Chemical properties
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