De(diethylaminoethyl-5-iodo) Amiodarone

CAS: 147030-50-0

Ref. TR-D228480

Product Information

• Name: De(diethylaminoethyl-5-iodo) Amiodarone
• Synonyms: Amiodarone Hydrochloride Imp. F (EP), Amiodarone Imp. F (EP), (2-Butylbenzofuran-3-yl)(4-hydroxy-3-iodophenyl)methanone, Amiodarone Hydrochloride Impurity F, Amiodarone Impurity F
• CAS: 147030-50-0

Description

Impurity Amiodarone EP Impurity F / Amiodarone USP Related Compound F
Applications De(diethylaminoethyl-5-iodo) Amiodarone (Amiodarone EP Impurity F) is an intermediate of Amiodarone (A632950), a non-selective ion channel blocker and an antiarrhythmic (class III).
References Bonati, M., et al.: J. Pharm. Sci., 73, 829 (1984), Plomp, T.A., Anal. Profiles Drug Subs., 20, 1 (1991), Chow, M., et al.: Ann. Pharmacother., 30, 637 (1996), Singh, B.N., et al.: Clin. Cardiol., 20, 608 (1997),

• Brand: TRC

Chemical properties

• Molecular weight: 420.24
• Formula: C₁₉H₁₇IO₃
• Color/Form: Neat
• InChI: InChI=1S/C19H17IO3/c1-2-3-7-17-18(13-6-4-5-8-16(13)23-17)19(22)12-9-10-15(21)14(20)11-12/h4-6,8-11,21H,2-3,7H2,1H3
• InChI key: InChIKey=SPJWRQCARFHMEB-UHFFFAOYSA-N
• SMILES: CCCCc1oc2ccccc2c1C(=O)c1ccc(O)c(I)c1