(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic Acid Triethylammonium Chloride Salt
CAS: 1015073-43-4
Ref. TR-D232080
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 2500µg | Discontinued |
Product Information
Name:
(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic Acid Triethylammonium Chloride Salt
Synonyms:
- PSI 7411 Triethylammonium Chloride Salt
Description:
Applications (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic Acid Triethylammonium Chloride Salt is an intermediate in the synthesis of (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Triethylammonium Salt (D235370), an impurity of Sofosbuvir (P839640). Sofosbuvir is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate.
References Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)
Notice:
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Brand:
TRC
Long term storage:
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Chemical properties
Molecular weight:
340.20 + 137.65
Formula:
C10H14FN2O8P•C6H16ClN
Color/Form:
white solid
SMILES:
CC[NH+](CC)CC.C[C@@]1(F)C(O)[C@H](COP(=O)(O)O)O[C@H]1n1ccc(=O)[nH]c1=O.[Cl-]
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