2-Deoxy-2-fluoro-a-D-arabinofuranosyl Bromide 3,5-Dibenzoate
CAS: 97614-44-3
Ref. TR-D235495
100mg | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued |
Product Information
- 2-Deoxy-2-fluoro-alpha-D-arabinofuranosyl Bromide Dibenzoate
- 2-Deoxy-1-α-bromo-2-β-fluoro-3,5-di-O-benzoyl-<span class="text-smallcaps">D</span>-ribofuranose
- 2-Deoxy-2-Fluoro-Alpha-D-Arabinofuranosyl Bromide 3,5-Dibenzoate
- 2-Deoxy-3,5-di-O-benzoyl-2-fluoro-a-D-arabinofuranosyl bromide
- α-<span class="text-smallcaps">D</span>-Arabinofuranosyl bromide, 2-deoxy-2-fluoro-, 3,5-dibenzoate
- α-<span class="text-smallcaps">D</span>-Arabinofuranosyl bromide, 2-deoxy-2-fluoro-, dibenzoate
Applications 2-Deoxy-2-fluoro-α-D-arabinofuranosyl Bromide 3,5-Dibenzoate, can be used in the synthesis of Clofarabine (C586890), which is a second generation purine nucleoside analog. It is also an antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic.
References Yaodong, Y., et al.: Jiefangjun Yaoxue Xuebao, 28, 218 (2012); Gandhi, V., et al.: Clin. Cancer Res., 9, 6335 (2003);