5'-Deoxy-5-fluoro-2',3'-O-(1-methylethylidene)-1-Alpha-D-ribosylcytosine

CAS: 66335-37-3

Ref. TR-D239925

Product Information

• Name: 5'-Deoxy-5-fluoro-2',3'-O-(1-methylethylidene)-1-Alpha-D-ribosylcytosine
• Synonyms: Furo[3,4-d]-1,3-dioxole, cytidine deriv. (ZCI), 5′-Deoxy-2′,3′-O-isopropylidene-5-fluorocytidine, 5'-Deoxy-5-fluoro-2',3'-O-isopropylidenecytidine, cytidine, 5'-deoxy-5-fluoro-2',3'-O-(1-methylethylidene)-, 5'-deoxy-5-fluoro-2',3'-O-(1-methylethylidene)cytidine

Description

Applications 5'-Deoxy-5-fluoro-2',3'-O-(1-methylethylidene)-1-α-D-ribosylcytosine is an intermediate in the synthesis of Capecitabine (C175650) related compounds.
References Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 285.27
• Formula: C₁₂H₁₆FN₃O₄
• Color/Form: White Solid
• InChI: InChI=1S/C12H16FN3O4/c1-5-7-8(20-12(2,3)19-7)10(18-5)16-4-6(13)9(14)15-11(16)17/h4-5,7-8,10H,1-3H3,(H2,14,15,17)/t5?,7?,8?,10-/m1/s1