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2'-Deoxy-6-thio Guanosine
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2'-Deoxy-6-thio Guanosine

CAS: 789-61-7

Ref. TR-D281650

10mg
237.00 €
100mg
1,599.00 €
Estimated delivery in United States, on Tuesday 28 May 2024

Product Information

Name:
2'-Deoxy-6-thio Guanosine
Synonyms:
  • 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione
  • 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-mercaptopurine
  • 2'-Deoxythioguanosine
  • 2'-Desoxy-6-thioguanosine
  • NSC 71261
  • TGdR
  • Thioguanine Deoxyriboside
  • β-Thioguanine Deoxyriboside
Description:

Applications Guanosine (G837900) derivative with cancer chemotherapeutic properties. It is involved in the inhibition of human RNase H-mediated RNA cleavage from DNA-RNA duplexes via incorporation into DNA.
References Momparler, R.L. et al.: Cancer Treat. Rep., 62, 135 (1978); Krynetskaia, N.F. et al.: Mol. Pharmacol., 56, 841 (1999);

Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
283.31
Formula:
C10H13N5O3S
Color/Form:
Yellow to Brown Solid
InChI:
InChI=1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5+,6+/m0/s1
InChI key:
InChIKey=SCVJRXQHFJXZFZ-KVQBGUIXSA-N
SMILES:
Nc1nc(=S)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c2[nH]1
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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