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Product Information
Name:
2'-Deoxy-6-thio Guanosine-13C, 15N2
Synonyms:
- 2-(15N)azanyl-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione
CAS:
Description:
Applications 2'-Deoxy-6-thio Guanosine-13C, 15N2 is labelled 2'-Deoxy-6-thio Guanosine (D281650) which is a Guanosine (G837900) derivative with cancer chemotherapeutic properties. It is involved in the inhibition of human RNase H-mediated RNA cleavage from DNA-RNA duplexes via incorporation into DNA.
References Momparler, R.L. et al.: Cancer Treat. Rep., 62, 135 (1978); Krynetskaia, N.F. et al.: Mol. Pharmacol., 56, 841 (1999)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
286.286
Formula:
C913CH13N315N2O3S
Color/Form:
Neat
InChI:
InChI=1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5+,6+/m0/s1/i10+1,11+1,14+1
InChI key:
InChIKey=SCVJRXQHFJXZFZ-CWPRTZMXSA-N
SMILES:
[15NH2][13c]1[nH]c2c(ncn2[C@H]2C[C@H](O)[C@@H](CO)O2)c(=S)[15n]1
MDL:
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Technical inquiry about: TR-D281652 2'-Deoxy-6-thio Guanosine-13C, 15N2
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