O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan
CAS: 2089065-77-8
Ref. TR-D282005
25mg | 2,178.00 € |
Product Information
- Sulfamide, N,N''-[1,2-ethanediylbis[oxy[5-(4-bromophenyl)-6,4-pyrimidinediyl]]]bis[N'-propyl-
- 5-(4-bromophenyl)-6-[2-[5-(4-bromophenyl)-6-(propylsulfamoylamino)pyrimidin-4-yl]oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine
Applications O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan is an impurity of Macitentan (M105005); a dual orally active and potent endothelin receptor antagonist used for pulmonary arterial hypertension.
References Emoto, N. Ensho to Men'eki, 20, 487 (2012); Bruderer, S., et al.: Xenobiotica, 42, 901 (2012); Bolli, M.H., et al.: J. Med. Chem., 55, 7849 (2012)
Chemical properties
Technical inquiry about: TR-D282005 O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan
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