N-Desacetyl-N,O-descarbonyl O-Acetyl Linezolid Dihydrochloride

CAS: 333753-71-2

Ref. TR-D288455

Product Information

• Name: N-Desacetyl-N,O-descarbonyl O-Acetyl Linezolid Dihydrochloride
• Synonyms: (S)-1-amino-3-((3-fluoro-4-morpholinophenyl)amino)propan-2-yl acetate hydrogen chloride

Description

Applications N-Desacetyl-N,O-descarbonyl O-Acetyl Linezolid Dihydrochloride is the salt form of D288280. N-Desacetyl-N,O-descarbonyl O-Acetyl Linezolid is an impurity of Linezolid (L466500); an oxazolidinone antimicrobial that inhibits bacterial mRNA translation.
References Brickner, S.J., et al.: J. Med. Chem., 39, 673 (1996); Ford, C.W., et al.: Antimicrob. Agents Chemother., 40, 1508 (1996); Rybak, M.J., et al.: Pharmacotherapy, 18, 456 (1998); Stevens, D.L., et al.: Clin. Infect. Dis., 34, 1481 (2002)

• Brand: TRC

Chemical properties

• Molecular weight: 384.27
• Formula: C₁₅H₂₄Cl₂FN₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C15H22FN3O3.2ClH/c1-11(20)22-13(9-17)10-18-12-2-3-15(14(16)8-12)19-4-6-21-7-5-19;;/h2-3,8,13,18H,4-7,9-10,17H2,1H3;2*1H/t13-;;/m0../s1
• InChI key: InChIKey=LHSLQFLZJIWZTD-ZDUSSCGKSA-N
• SMILES: CC(=O)O[C@@H](CN)CNc1ccc(N2CCOCC2)c(F)c1