4-Desacetamido-4-fluoro Andarine

CAS: 401900-41-2

Ref. TR-D289530

Product Information

• Name: 4-Desacetamido-4-fluoro Andarine
• Synonyms: (2S)-3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide, SARM S 1, Propanamide, 3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-, (2S)-, N-[4-Nitro-3-(trifluoromethyl)phenyl]-(2S)-3-(4-fluorophenoxy)-2-hydroxy-2-methylpropanamide, ((S)-3-(4-Fluorophenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethylphenyl)propionamide, (2S)-3-(4-Fluorophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

Description

Applications 4-Desacetamido-4-fluoro Andarine is a Selective Androgen Receptor Modulator (SARM) that has potential use for treatment of androgen related diseases such as muscle wasting and osteoporosis. 4-Desacetamido-4-fluoro Andarine is also a derivative of Andarine (A637470), a non-steroidal SARM that is used by athletes to enhance performance.
References Jones, A., et al.: Endocrinology, 150, 385 (2009); Marhefka, C., et al.: J. Med. Chem., 47, 993 (2004); Thomas, A., et al.: Rapid Comm. Mass Spec., 24, 1124 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 402.30
• Formula: C₁₇H₁₄F₄N₂O₅
• Color/Form: Neat
• InChI: InChI=1S/C17H14F4N2O5/c1-16(25,9-28-12-5-2-10(18)3-6-12)15(24)22-11-4-7-14(23(26)27)13(8-11)17(19,20)21/h2-8,25H,9H2,1H3,(H,22,24)/t16-/m0/s1
• SMILES: C[C@](O)(COc1ccc(F)cc1)C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1