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3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib
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3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib

CAS: 1603814-04-5

Ref. TR-D289540

1g
2,079.00 €
100mg
319.00 €
Estimated delivery in United States, on Monday 17 Jun 2024

Product Information

Name:
3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib
Synonyms:
  • 4-Quinazolinamine
  • N-(4-chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-
  • Gefitinib Imp. B (EP)
  • Gefitinib Impurity B
Description:

Applications 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib is an impurity of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).
References Lynch, T.J., et al.: N. Engl. J. Med., 350, 2129 (2004); Engelman, J.A., et al.: Science, 316, 1039 (2007); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003)

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
446.90
Formula:
C22H24ClFN4O3
Color/Form:
Off White Solid
InChI:
InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-17(23)18(24)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
InChI key:
InChIKey=WTDLLXPLBLPTEP-UHFFFAOYSA-N
SMILES:
COc1cc2ncnc(Nc3ccc(Cl)c(F)c3)c2cc1OCCCN1CCOCC1
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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