N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride

CAS: 133216-45-2

Ref. TR-D289575

Product Information

• Name: N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
• Synonyms: 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-cyclohexyl-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-, 4-Azaandrost-1-ene-17-carboxamide, N-cyclohexyl-3-oxo-, (5a,17ß)-, 1H-Indeno[5,4-f]quinoline, 4-azaandrost-1-ene-17-carboxamide deriv., N-Cyclohexyl-3-oxo-4-aza-5a-androst-1-ene-17ß-carboxamide, N-Cyclohexyl-3-oxo-4-aza-5a-androst-1-ene-17ß-carboxamide
• CAS: 133216-45-2

Description

Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.
References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)

• Brand: TRC

Chemical properties

• Molecular weight: 398.58
• Formula: C₂₅H₃₈N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C25H38N2O2/c1-24-14-12-19-17(8-11-21-25(19,2)15-13-22(28)27-21)18(24)9-10-20(24)23(29)26-16-6-4-3-5-7-16/h13,15-21H,3-12,14H2,1-2H3,(H,26,29)(H,27,28)/t17-,18-,19-,20+,21+,24-,25+/m0/s1
• InChI key: InChIKey=NPSWHDAHNWWMEG-UHFFFAOYSA-N
• SMILES: C=CCCC(N)C(=O)O