6-O-Desmethoxyethyl-6-O-chloroethyl Erlotinib Hydrochloride
CAS: 183320-04-9
Ref. TR-D290370
| 1mg | Discontinued | ||
| 10mg | Discontinued |
Product Information
Name:
6-O-Desmethoxyethyl-6-O-chloroethyl Erlotinib Hydrochloride
Synonyms:
- 6-(2-Chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)-4-quinazolinamine Hydrochloride (1:1)
- 6-(2-Chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride
- 4-Quinazolinamine, 6-(2-chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)-, hydrochloride (1:1)
- 4-Quinazolinamine, 6-(2-chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)-, monohydrochloride
Description:
Applications 6-O-Desmethoxyethyl-6-O-chloroethyl Erlotinib hydrochloride is a derivative of Erlotinib (E625000), an epidermal growth factor receptor inhibitor and tyrosine kinase inhibitor that is used to treat patients with lung cancer.
References Herbst, R., et al.: J. Clin. Oncol., 23, 5892 (2005); Pérez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004); Shepherd, F., et al.: New Engl. J. Med., 353, 123 (2005)
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
434.32
Formula:
C21H21Cl2N3O3
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/CH4/h1H4
InChI key:
InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES:
C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCCl)cc23)c1.Cl
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