S-Desethylpiperidino S-[2-Carboxyl-2-oxo-ethyl-(2-aminoethyl)amino] Vardenafil

CAS: 448184-56-3

Ref. TR-D290970

Product Information

• Name: S-Desethylpiperidino S-[2-Carboxyl-2-oxo-ethyl-(2-aminoethyl)amino] Vardenafil
• Synonyms: 2-[[2-[[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]amino]ethyl]amino]-2-oxoacetic Acid, [[2-[[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]amino]ethyl]amino]oxoacetic Acid, Vardenafil Oxoacetic Acid Impurity

Description

Applications S-Desethylpiperidino S-[2-Carboxyl-2-oxo-ethyl-(2-aminoethyl)amino] Vardenafil is an impurity of Vardenafil (V098001, 2HCl); a selective phosphodiesterase type 5 (PDE5) inhibitor.
References Bischoff, E., et al.: J. Urol., 165, 1316 (2001); Kim, N.N., et al.: Life Sci., 69, 2249 (2001); Kendirci, M., et al.: Expert Opin. Pharmacother., 5, 923 (2004)

• Brand: TRC

Chemical properties

• Molecular weight: 506.53
• Formula: C₂₁H₂₆N₆O₇S
• Color/Form: Off White Solid
• InChI: InChI=1S/C21H26N6O7S/c1-4-6-16-24-12(3)17-19(28)25-18(26-27(16)17)14-11-13(7-8-15(14)34-5-2)35(32,33)23-10-9-22-20(29)21(30)31/h7-8,11,23H,4-6,9-10H2,1-3H3,(H,22,29)(H,30,31)(H,25,26,28)
• InChI key: InChIKey=IYBDOKDAJOBYNZ-UHFFFAOYSA-N
• SMILES: CCCc1nc(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)NCCNC(=O)C(=O)O)ccc3OCC)nn12