N-Des(4-methylbenzenesulfonamide) 4’-Nitro Tolafentrine
CAS: 35134-99-7
Ref. TR-D291140
| 5mg | Discontinued | ||
| 500µg | Discontinued | ||
| 2500µg | Discontinued |
Product Information
Name:
N-Des(4-methylbenzenesulfonamide) 4’-Nitro Tolafentrine
Synonyms:
- (10bS)-8,9-Dimethoxy-2-methyl-6-(4-nitrophenyl)-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridine
- cis-1,2,3,4,4a,10b-Hexahydro-8,9-dimethoxy-2-methyl-6-(4-nitrophenyl)-benzo[c][1,6]naphthyridine
Description:
Applications N-Desmethylbenzenesulfonamide 4’-Nitro Tolafentrine is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension.
References Huxtable, R., et al.: Pharmacol. Ther., 47, 371 (1990), Tanaka, K., et al.: Cancer Res., 55, 2927 (1995), Wagner, R., et al.: J. Pharmacol. Exp. Ther., 282, 1650 (1997), Cowan, K., et al.: Nat. Med., 6, 698 (2000), Shankavaram, U., et al.: J. Biol. Chem., 276, 19027 (2001),
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
381.43
Formula:
C21H23N3O4
Color/Form:
Yellow Solid
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