Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(pyrrolidin-2,5-dion-1-yl) Afatinib
Ref. TR-D291238
| 25mg | Discontinued | ||
| 50mg | Discontinued | ||
| 100mg | Discontinued |
Product Information
Name:
Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(pyrrolidin-2,5-dion-1-yl) Afatinib
Description:
Applications Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(pyrrolidin-2,5-dion-1-yl) Afatinib is an intermediate in the synthesis of Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(5-Hydroxy-pyrrolidin-2-on-1-yl) Afatinib which is a derivative compound of Afatinib (A355300) used for the treatment of breast cancer and other cell lunger cancer related diseases.
References Nancy, U., et al.: Breast Cancer Res. Treat., 133, 1057 (2012)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
456.85
Formula:
C22H18ClFN4O4
Color/Form:
Yellowish Solid
InChI:
InChI=1S/C22H18ClFN4O4/c23-15-7-12(1-2-16(15)24)27-22-14-8-18(28-20(29)3-4-21(28)30)19(9-17(14)25-11-26-22)32-13-5-6-31-10-13/h1-2,7-9,11,13H,3-6,10H2,(H,25,26,27)/t13-/m0/s1
InChI key:
InChIKey=ZDTFMPXQUSBYRL-UUOKFMHZSA-N
SMILES:
Nc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1
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