Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(5-Amino-pyrrolidin-2-on-1-yl) Afatinib
CAS: 2223677-58-3 2413212-19-6
Ref. TR-D291248
| 10mg | 244.00 € | ||
| 25mg | 534.00 € | ||
| 50mg | 1,010.00 € |
Estimated delivery in United States, on Friday 28 Jun 2024
Product Information
Name:
Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(5-Amino-pyrrolidin-2-on-1-yl) Afatinib
Synonyms:
- 5-amino-1-(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)pyrrolidin-2-one
Description:
Applications Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(5-Amino-pyrrolidin-2-on-1-yl) Afatinib is an impurity in the synthesis of Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(5-Hydroxy-pyrrolidin-2-on-1-yl) Afatinib which is a derivative compound of Afatinib (A355300) used for the treatment of breast cancer and other cell lunger cancer related diseases.
References Nancy, U., et al.: Breast Cancer Res. Treat., 133, 1057 (2012)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
457.89
Formula:
C22H21ClFN5O3
InChI:
InChI=1S/C22H21ClFN5O3/c23-15-7-12(1-2-16(15)24)28-22-14-8-18(29-20(25)3-4-21(29)30)19(9-17(14)26-11-27-22)32-13-5-6-31-10-13/h1-2,7-9,11,13,20H,3-6,10,25H2,(H,26,27,28)/t13-,20?/m0/s1
InChI key:
InChIKey=IHPKGUQCSIINRJ-NTMALXAHSA-N
SMILES:
C=C/C(C)=C\CC=C(C)C
MDL:
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