Estimated delivery in United States, on Wednesday 12 Jun 2024
Product Information
Name:
O-Desmethyl Midostaurin
Synonyms:
- N-[(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl]-N-methylbenzamide
- CGP 62221
- O-Desmethyl-PKC 412
CAS:
Description:
Stability Hygroscopic
Applications O-Desmethyl Midostaurin is a metabolite of Midostaurin (M343760), a compound shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit.
References Tahtouh, T., et al.: J. Med. Chem., 55, 9312 (2012); Pedeboscq, S., et al.: PLoS. One., 7, 36811 (2012);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
556.61
Formula:
C34H28N4O4
Color/Form:
Neat
InChI:
InChI=1S/C34H28N4O4/c1-34-31(39)24(36(2)33(41)18-10-4-3-5-11-18)16-25(42-34)37-22-14-8-6-12-19(22)27-28-21(17-35-32(28)40)26-20-13-7-9-15-23(20)38(34)30(26)29(27)37/h3-15,24-25,31,39H,16-17H2,1-2H3,(H,35,40)/t24-,25?,31-,34+/m1/s1
InChI key:
InChIKey=PXOCRDZEEXVZQC-AFUPZKSLSA-N
SMILES:
CN(C(=O)c1ccccc1)[C@@H]1C[C@H]2O[C@@](C)([C@@H]1O)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4
MDL:
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EINECS:
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HS code:
Technical inquiry about: TR-D291400 O-Desmethyl Midostaurin
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