(R)-(+)-O-Desmethyl Carvedilol

CAS: 123372-14-5

Ref. TR-D291480

Product Information

• Name: (R)-(+)-O-Desmethyl Carvedilol
• Synonyms: (R)-2-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]phenol, (R)-(+)-Desmethyl Carvedilol, 2-[2-[[(2R)-3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]phenol, Phenol, 2-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-, (R)-
• CAS: 123372-14-5

Description

Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α-1-blocking activity. [α]D= +18.7 (c= 0.1 methanol)
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),

• Brand: TRC

Chemical properties

• Molecular weight: 392.45
• Formula: C₂₃H₂₄N₂O₄
• Color/Form: Off-White to Pale Beige Solid
• InChI: InChI=1S/C23H24N2O4/c26-16(14-24-12-13-28-21-10-4-3-9-20(21)27)15-29-22-11-5-8-19-23(22)17-6-1-2-7-18(17)25-19/h1-11,16,24-27H,12-15H2/t16-/m1/s1
• InChI key: InChIKey=XAUKPPPYYOKVQJ-MRXNPFEDSA-N
• SMILES: Oc1ccccc1OCCNC[C@@H](O)COc1cccc2[nH]c3ccccc3c12