Desmethyl Icaritin

CAS: 28610-31-3

Ref. TR-D291760

Product Information

• Name: Desmethyl Icaritin
• Synonyms: 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one, 4'-Desmethylicaritin, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-, 4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)- (9CI), 8-C-Prenylkaempferol, 8-Prenylkaempferol, De-O-methylanhydroicaritin, Desmethylanhydroicaritin, Desmethylicaritin, Flavone, 3,4′,5,7-tetrahydroxy-8-(3-methyl-2-butenyl)-, Flavone,3,4',5,7-tetrahydroxy-8-(3-methyl-2-butenyl)- (8CI), Noranhydroicaritin
• CAS: 28610-31-3

Description

Applications A metabolite of Icariin. Icaritin and Desmethylicaritin, two metabolites of Icariin, dramatically inhibit the growth of most malignant cells. They also have significant antiangiogenesis properties, inhibiting or eliminating entirely the development of new malignant cells.
References Carmichael, J; Cancer Res 1987, 47, 943,,,Franke, T; Science 1997, 275, 665,,,Kowalski, J; Pharmacol Rep 2005, 57, 390,,,Lee, G; Eur J Pharmacol 2006, 551, 143,,,

• Brand: TRC

Chemical properties

• Molecular weight: 354.35
• Formula: C₂₀H₁₈O₆
• Color/Form: Neat
• InChI: InChI=1S/C20H18O6/c1-10(2)3-8-13-14(22)9-15(23)16-17(24)18(25)19(26-20(13)16)11-4-6-12(21)7-5-11/h3-7,9,21-23,25H,8H2,1-2H3
• InChI key: InChIKey=NADCVNHITZNGJU-UHFFFAOYSA-N
• SMILES: CC(C)=CCc1c(O)cc(O)c2c(=O)c(O)c(-c3ccc(O)cc3)oc12