Desmethyl Nafcillin Sodium Salt

CAS: 1104-49-0

Ref. TR-D292740

Product Information

• Name: Desmethyl Nafcillin Sodium Salt
• Synonyms: (2S,5R,6R)-6-[(2-methoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;sodium hydride, 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-(2-methoxy-1-naphthamido)-3,3-dimethyl-7-oxo-, monosodium salt(7CI,8CI), 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2-methoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodiumsalt, (2S,5R,6R)- (9CI), 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2-methoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodiumsalt, [2S-(2a,5a,6b)]-, Brl 1336

Description

Applications Desmethyl Nafcillin Sodium Salt is derived from (+)-6-Aminopenicillanic Acid (A618895), which is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the preparation of numerous semisynthetic penicillins.
References Zel'tser, I.Z. et al.: Gig. Truda Prof. Zabol., 5, 59 (1983); Hamilton-Miller, J.M.T.: Int. J. Antimicrob. Agents, 31, 189 (2008); Novikova, N.D. et al.: Mikol. Fitopatol., 7, 101 (1973)

• Brand: TRC

Chemical properties

• Molecular weight: 423.438
• Formula: C₂₀H₂₀N₂O₅S·Na
• Color/Form: Neat
• InChI: InChI=1S/C20H20N2O5S.Na.H/c1-20(2)15(19(25)26)22-17(24)14(18(22)28-20)21-16(23)13-11-7-5-4-6-10(11)8-9-12(13)27-3;;/h4-9,14-15,18H,1-3H3,(H,21,23)(H,25,26);;/t14-,15+,18-;;/m1../s1
• InChI key: InChIKey=RUVCZVUDVRMREH-GDUZTWOJSA-N
• SMILES: COc1ccc2ccccc2c1C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12.[Na]