Estimated delivery in United States, on Wednesday 15 Jan 2025
Product Information
Name:
7-Demethyl Ivabradine
Controlled Product
Synonyms:
- 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7-hydroxy-8-methoxy-2H-3-Benzazepin-2-one
- 2H-3-Benzazepin-2-one, 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7-hydroxy-8-methoxy-
- 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7-hydroxy-8-methoxy-2H-3-benzazepin-2-one
Description:
Applications 7-Demethyl Ivabradine is an impurity of Ivabradine (I940500), which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.
References Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
454.56
Formula:
C26H34N2O5
Color/Form:
Neat
InChI:
InChI=1S/C26H34N2O5/c1-27(16-20-10-19-13-24(32-3)25(33-4)15-21(19)20)7-5-8-28-9-6-17-11-22(29)23(31-2)12-18(17)14-26(28)30/h11-13,15,20,29H,5-10,14,16H2,1-4H3/t20-/m1/s1
InChI key:
InChIKey=QBMUBWFMPCQUGQ-HXUWFJFHSA-N
SMILES:
COc1cc2c(cc1O)CCN(CCCN(C)C[C@H]1Cc3cc(OC)c(OC)cc31)C(=O)C2
MDL:
Melting point:
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Flash point:
Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-D292980 7-Demethyl Ivabradine
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