Desoxochlordiazepoxide

CAS: 4393-72-0

Ref. TR-D296850

Product Information

• Name: Desoxochlordiazepoxide
• Synonyms: 7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine, 7-Chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine, 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-

Description

Applications Desoxochlordiazepoxide is a benzodiazepine and a degradation product of Chlordiazepoxide (C327050), and can be found in liver homogenates spiked with Chlordiazepoxide. Desoxochlordiazepoxide has anticonvulsant effects. Desoxochlordiazepoxide is also an intermediate in the synthesis of 8-Chloro-1-methyl-6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepine (C369430), which is an impurity of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.
References Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000); Bogatskii, A., et al.: Fiz. Akt. Vesh., 9, 9 (1977); Entwistle, N., et al.: J. Forensic Sci. Soc., 26, 45 (1986)

• Brand: TRC

Chemical properties

• Molecular weight: 283.76
• Formula: C₁₆H₁₄ClN₃
• Color/Form: Neat
• InChI: InChI=1S/C16H14ClN3/c1-18-15-10-19-16(11-5-3-2-4-6-11)13-9-12(17)7-8-14(13)20-15/h2-9H,10H2,1H3,(H,18,20)
• InChI key: InChIKey=FAMNQSVPYUAUAF-UHFFFAOYSA-N
• SMILES: CNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1