Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt

Ref. TR-D297044

Product Information

• Name: Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt
• Synonyms: propan-2-yl-d7 (((l5-azaneyl)oxy)((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)-L-alaninate

Description

Stability Unstable in Solution
Applications Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt is labeled form of Desphenyl Tenofovir Alafenamide (D297043), which belongs to a group of tenofovir diesters compounds, which can inhibit HIV-1 virus replication. Desphenyl Tenofovir Alafenamide can also be used to investigate the effect of oral absorption and lymphoid cell loading of GS-7340 (a prodrug of tenofovir)
References You, G., et al.: PCT Int. Appl. WO 2014026582 A1 2014022 (2014); Babusis, D., et al.: Mol. Pharm. 10, 459 (2013)

• Brand: TRC

Chemical properties

• Molecular weight: 424.44
• Formula: C₁₅H₂₁D₇N₇O₅P
• Color/Form: Neat
• InChI: InChI=1S/C15H28N7O5P/c1-9(2)26-15(23)11(4)21-28(24,27-17)8-25-10(3)5-22-7-20-12-13(16)18-6-19-14(12)22/h6-7,9-11H,5,8H2,1-4H3,17H4,(H,21,24)(H2,16,18,19)/t10-,11+,28?/m1/s1/i1D3,2D3,9D
• InChI key: InChIKey=WOZAIDHMITUIMO-AAZSQCCXSA-N