Destearaldehyde Beta-Galactosyl-C18-ceramide Tetraacetate

Ref. TR-D297485

Product Information

• Name: Destearaldehyde Beta-Galactosyl-C18-ceramide Tetraacetate
• Synonyms: (2R,3S,4S,5R,6R)-2-(Acetoxymethyl)-6-(((2S,3R,E)-2-amino-3-hydroxyoctadec-4-en-1-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate

Description

Stability Moisture Sensitive
Applications Destearaldehyde β-Galactosyl-C18-ceramide Tetraacetate is an intermediate formed in the synthesis of β-Galactosyl-C18-ceramide (G184960), which is a galactosylceramides that plays an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma.
References Morita, M., et al.: J. Med. Chem., 38, 2176 (1995); Sakai, T., et al.: J. Med. Chem., 42, 1836 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 629.78
• Formula: C₃₂H₅₅NO₁₁
• Color/Form: Neat
• InChI: InChI=1S/C32H55NO11/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-27(38)26(33)20-40-32-31(43-25(5)37)30(42-24(4)36)29(41-23(3)35)28(44-32)21-39-22(2)34/h18-19,26-32,38H,6-17,20-21,33H2,1-5H3/b19-18+/t26-,27+,28+,29?,30?,31?,32+/m0/s1
• SMILES: CCCCCCCCCCCC1=[N+](Cc2ccc(C(C)(C)C)cc2)CCc2cc(F)ccc21.[Br-]