Des-(3-Oxo-3,4-dihydrogen) 3,6-Difluoro Favipiravir

CAS: 356783-29-4

Ref. TR-D356785

Product Information

• Name: Des-(3-Oxo-3,4-dihydrogen) 3,6-Difluoro Favipiravir
• Synonyms: 2-Pyrazinecarboxamide, 3,6-difluoro-, Pyrazinecarboxamide, 3,6-difluoro- (9CI), 3,6-Difluoro-2-pyrazinecarboxamide, 3,6-Difluoropyrazine-2-carboxamide, Pyrazinecarboxamide, 3,6-difluoro-, Pyrazinecarboxamide,3,6-difluoro- (9CI), 2-Pyrazinecarboxamide, 3,6-difluoro-

Description

Applications Des-(3-Oxo-3,4-dihydrogen) 3,6-Difluoro Favipiravir is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.
References Oestereich, L., et al.: Antiviral Res., 105, 17 (2014); Baranovich, T., et al.: J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 159.0936
• Formula: C₅H₃F₂N₃O
• Color/Form: Neat
• InChI: InChI=1S/C5H3F2N3O/c6-2-1-9-4(7)3(10-2)5(8)11/h1H,(H2,8,11)
• InChI key: InChIKey=WIQUNYNMYIJSCV-UHFFFAOYSA-N
• SMILES: NC(=O)c1nc(F)cnc1F