2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2,15N

CAS: 2387-48-6

Ref. TR-D416351

Product Information

• Name: 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2,15N
• Synonyms: 2,6-Diamino-5-nitroso-4(3H)-pyrimidinone-13C2,15N, 2,6-Diamino-5-nitroso-4(1H)-pyrimidinone-13C2,15N,2,6-Diamino-5-nitroso-4-pyrimidinol-13C2,15N, 2,6-Diamino-5-nitroso-4(3H)-pyrimidinone-13C2,15N,2,4-Diamino-5-nitroso-6-hydroxypyrimidine-13C2,15N,2,4-Diamino-5-nitroso-6-pyrimidinol-13C2,15N,2,4-Diamino-6-hydroxy-5-nitrosopyrimidine-13C2,15N,NSC 677503-13C2,15N,NSC 83516-13C2,15N,NSC 9301-13C2,15N,2,6-Diamino-5-nitroso-4-pyrimidinol-13C2,15N, 2,4-Diamino-5-nitroso-6-hydroxypyrimidine, 2,4-Diamino-5-nitroso-6-pyrimidinol, 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine, 2,6-Diamino-5-nitroso-1,4-dihydropyrimidin-4-one, 2,6-Diamino-5-nitroso-1H-pyrimidin-4-one, 2,6-Diamino-5-nitroso-4(3H)-pyrimidinone, 2,6-Diamino-5-nitroso-4-pyrimidinol, 2,6-diamino-5-nitrosopyrimidin-4(1H)-one, 4(1H)-Pyrimidinone, 2,6-diamino-5-nitroso-, 4(1H)-Pyrimidinone, 2,6-diamino-5-nitroso- (9CI), 4(3H)-Pyrimidinone, 2,6-diamino-5-nitroso-, 4-Pyrimidinol, 2,6-diamino-5-nitroso-, 4-Pyrimidol, 2,6-diamino-5-nitroso-, Ai3-61770, NSC 677503, NSC 83516, Nsc 9301

Description

Applications 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2,15N is an intermediate in the synthesis of labelled Guanine (G836000). Guanine is on one of the five nucleobases incorporated into biological nucleic acids. Guanine, along with adenine and cytosine, is present in both DNA and RNA, whereas thymine is usually seen only in DNA, and uracil only in RNA.
References Geslain, R., et al.: J. Biol. Chem., 284, 27760 (2009); Manini, P., et al.: Toxicol. Lett., 190, 41 (2009); Gong, B., et al.: Biochem., 48, 11961 (2009); Sugimoto, M., et al.: J. Agric. Food Chem., 58, 374 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 158.094
• Formula: C₂C₂H₅NN₄O₂
• Color/Form: Neat
• InChI: InChI=1S/C4H5N5O2/c5-2-1(9-11)3(10)8-4(6)7-2/h(H5,5,6,7,8,10)/i1+1,2+1,9+1
• InChI key: InChIKey=HVMRLFSFHWCUCG-SKBHVPMCSA-N
• SMILES: Nc1nc(O)[13c]([15N]=O)[13c](N)n1