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10,11-Dibromo10,11-dihydro-5-dibenzosuberenone
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10,11-Dibromo10,11-dihydro-5-dibenzosuberenone

CAS: 39654-52-9

Ref. TR-D417337

Estimated delivery in United States, on Monday 29 Nov 2021

Product Information

Name:
10,11-Dibromo10,11-dihydro-5-dibenzosuberenone
Synonyms:
  • rel-(10R,11R)-10,11-Dibromo-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one
  • 10,11-dibromo-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one
Description:
Applications 10,11-Dibromo10,11-dihydro-5-dibenzosuberenone is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).
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Chemical properties

Molecular weight:
366.05
Formula:
C15H10Br2O
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Hazard Info

UN Number:
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Technical inquiry about: TR-D417337 10,11-Dibromo10,11-dihydro-5-dibenzosuberenone

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