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(R)-Diphenyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
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(R)-Diphenyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

CAS: 342631-41-8

Ref. TR-D431035

25mg
346.00 €
100mg
1,208.00 €
250mg
2,353.00 €
Estimated delivery in United States, on Tuesday 11 Feb 2025

Product Information

Name:
(R)-Diphenyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Controlled Product
Synonyms:
  • [(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid
  • Diphenyl Ester
Description:

Applications (R)-Diphenyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate is a reagent for the synthesis of amidate prodrugs of PMEA and PMPA. Also functions as a reagent in the preparation of tenofovir alafenamide fumarate impurity.
References Ballatore, C., et al.: Bioorg. Med. Chem. Lett., 11, 1053 (2001); Chen, G., et al.: From Faming Zhuanli Shenqing (2016), CN 105330700 A 20160217

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
439.4
Formula:
C21H22N5O4P
Color/Form:
White To Beige
InChI:
InChI=1S/C21H22N5O4P/c1-16(12-26-14-25-19-20(22)23-13-24-21(19)26)28-15-31(27,29-17-8-4-2-5-9-17)30-18-10-6-3-7-11-18/h2-11,13-14,16H,12,15H2,1H3,(H2,22,23,24)/t16-/m1/s1
InChI key:
InChIKey=XWTDSRIRFPGRAW-MRXNPFEDSA-N
SMILES:
C[C@H](Cn1cnc2c(N)ncnc21)OCP(=O)(Oc1ccccc1)Oc1ccccc1
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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