1-(2,6-Dichloro-4-hydroxphenyl)-1,3-dihydroindol-2-one-13C6

CAS: 73328-71-9

Ref. TR-D434674

Product Information

• Name: 1-(2,6-Dichloro-4-hydroxphenyl)-1,3-dihydroindol-2-one-13C6
• Synonyms: 1-(2,6-dichloro-4-hydroxyphenyl)indolin-2-one-3a,4,5,6,7,7a-13C6

Description

Applications 1-(2,6-Dichloro-4-hydroxphenyl)-1,3-dihydroindol-2-one-13C6 is an intermediate in synthesizing 4’-Hydroxy Diclofenac-13C6, a labelled metabolite of Diclofenac, which is a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.
References Kretz-Rommel, A., et al.: Toxicol. Appl. Pharmacol., 120, 155 (1993); Petronilli, V., et al.: J. Biol. Chem., 269, 16638 (1994); Bort, R., et al.: J. Pharmacol. Exp. Ther., 288, 65 (1998; Poon, G., et al.: Drug Metab. Dispos., 29, 1608 (2001)

• Brand: TRC

Chemical properties

• Molecular weight: 300.09
• Formula: C₈C₆H₉Cl₂NO₂
• Color/Form: Neat
• InChI: InChI=1S/C14H9Cl2NO2/c15-10-6-9(18)7-11(16)14(10)17-12-4-2-1-3-8(12)5-13(17)19/h1-4,6-7,18H,5H2/i1+1,2+1,3+1,4+1,8+1,12+1
• InChI key: InChIKey=KXOJXWNARBQHNX-UHFFFAOYSA-N
• SMILES: Clc1ccc(Oc2cc(Cl)c(Cl)cc2Cl)cc1