![4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile](https://static.cymitquimica.com/products/TR/img/D435380.png "Click to enlarge")
4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile
CAS: 1391063-17-4
Ref. TR-D435380
| 10mg | 93.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 719.00 € |
Product Information
- Des(2,4-dichloro-5-methoxyphenyl) 3,5-Dichloro-4-methoxyphenyl Bosutinib
Applications Kinase inhibitors, such as bosutinib, are useful cancer drugs but their target specificity is not fully understood. 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile has been employed as a clinical kinase inhibitor bosutinib to elucidate the recognition mechanism between the ATP-binding site and the compound.
References Levinson, N. M. and Boxer, S. G., Nat Chem. Biol 10, 127 (2014); Yen, T. and Beeharry, N., PCT Int. Appl. WO 2013187967 A1 20131219 (2013);
Chemical properties
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