5,6-Dichloropurine-1-b-D-ribofuanosyl-H-benzimidazole

CAS: 53-85-0

Ref. TR-D435820

Product Information

• Name: 5,6-Dichloropurine-1-b-D-ribofuanosyl-H-benzimidazole
• Synonyms: (2R,3R,4S,5R)-2-(5,6-dichlorobenzimidazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol, 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-5,6-dichlorobenzimidazole, 1H-Benzimidazole, 5,6-dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 5,6-Dichloro-1-(β-<span class="text-smallcaps">D</span>-ribofuranosyl)benzimidazole, 5,6-Dichloro-1-b-D-ribofuranosylbenzimidazole, 5,6-Dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole, 5,6-Dichlorobenzimidazole 1-beta-D-ribofuranoside, 5,6-Dichlorobenzimidazole 1-β-<span class="text-smallcaps">D</span>-ribofuranoside, 5,6-Dichlororibofuranosylbenzimidazole, 5,6-dichloro-1-(beta-D-ribofuranosyl)-1H-benzimidazole, 5,6-dichloro-1-[(2xi)-beta-D-threo-pentofuranosyl]-1H-benzimidazole, 5,6-dichloro-1-pentofuranosyl-1H-benzimidazole, Benzimidazole, 5,6-dichloro-1-<span class="text-smallcaps">D</span>-ribofuranosyl-, Benzimidazole, 5,6-dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, NSC 401575, Nqz-002
• CAS: 53-85-0

Description

Applications An inhibitor of RNA synthesis (causes premature termination of transcription).
References Braedlye, J. and Sporns, O.: Brain Res., 815, 140 (1999), Ljungman, M., et al.: Oncogene, 18, 583 (1999), Roele, R.H., et al.: Oncogene, 18, 5765 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 319.14
• Formula: C₁₂H₁₂Cl₂N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C12H12Cl2N2O4/c13-5-1-7-8(2-6(5)14)16(4-15-7)12-11(19)10(18)9(3-17)20-12/h1-2,4,9-12,17-19H,3H2/t9-,10-,11-,12-/m1/s1
• InChI key: InChIKey=XHSQDZXAVJRBMX-DDHJBXDOSA-N
• SMILES: OC[C@H]1O[C@@H](n2cnc3cc(Cl)c(Cl)cc32)[C@H](O)[C@@H]1O