6alpha,9alpha-Difluoroprednisolone 21-Acetate

CAS: 52-70-0

Ref. TR-D446325

Product Information

• Name: 6alpha,9alpha-Difluoroprednisolone 21-Acetate
• Synonyms: (6a,11ß)-21-(Acetyloxy)-6,9-difluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione, 6a,9-Difluoro-11ß,17,21-trihydroxypregna-1,4-diene-3,20-dione, (6Alpha,11Beta)-6,9-Difluoro-11,17-Dihydroxy-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate, (6α,11β)-21-(Acetyloxy)-6,9-difluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione, 200-150-9, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11,17-dihydroxy-, (6α,11β)-, Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,17,21-trihydroxy-, 21-acetate, Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-, 21-acetate

Description

Applications 6α,9α-​Difluoroprednisolone 21-Acetate, is an impurity of Difluprednate (D445925), which is shown to have antiinflammatory activity.
References Toscano L., et al.: J. Med. chem., 20, 213 (1977);

• Brand: TRC

Chemical properties

• Molecular weight: 438.46
• Formula: C₂₃H₂₈F₂O₆
• Color/Form: White To Off-White
• InChI: InChI=1S/C23H28F2O6/c1-12(26)31-11-19(29)22(30)7-5-14-15-9-17(24)16-8-13(27)4-6-20(16,2)23(15,25)18(28)10-21(14,22)3/h4,6,8,14-15,17-18,28,30H,5,7,9-11H2,1-3H3/t14-,15-,17-,18-,20-,21-,22-,23-/m0/s1
• InChI key: InChIKey=LAAFISZDLHQNFS-WGFKBPOKSA-N
• SMILES: CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C