5,6-Dihydro-5-aza-2’-deoxycytidine (may contain up to 15% inorganics)
CAS: 114522-16-6
Ref. TR-D447775
| 5mg | 175.00 € |
Estimated delivery in United States, on Tuesday 4 Jun 2024
Product Information
Name:
5,6-Dihydro-5-aza-2’-deoxycytidine (may contain up to 15% inorganics)
Synonyms:
- 4-Amino-1-(2-deoxy-ß-D-erythro-pentofuranosyl)-3,6-dihydro-1,3,5-triazin-2(1H)-one
- 2'-Deoxy-5,6-dihydro-5-azacytidine
- KP 1212
- 6-Amino-3-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-1,3,5-triazin-2(1H)-one
- 4-Amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,6-dihydro-1,3,5-triazin-2-one
CAS:
Description:
Applications 5,6-Dihydro-5-aza-2’-deoxycytidine is a selective mutagen that induces A-to-G and G-to-A mutations in the genome of replicating HIV. First-in-class lethal mutagen of HIV-1; Anti-HIV inhibitor.
References Peng, C. S., et al.: Proc. Natl. Acad. Sci. U.S.A., 112, 3229-3234 (2015); Rawson, J. M., et al.: Bioorg. Med. Chem., 21, 7222-7228 (2013); Murakami, E., et al.: Antiviral Res., 67, 10-17 (2005)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
230.22
Formula:
C8H14N4O4
Color/Form:
Neat
InChI:
InChI=1S/C8H14N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h4-6,13-14H,1-3H2,(H3,9,10,11,15)/t4-,5+,6+/m0/s1
InChI key:
InChIKey=LAOLDMMWVYDDID-KVQBGUIXSA-N
SMILES:
NC1=NC(=O)N([C@H]2C[C@H](O)[C@@H](CO)O2)CN1
MDL:
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