Dihydro Artemisinin Beta-D-Glucuronide (Mixture of Isomers)

CAS: 198976-06-6

Ref. TR-D448370

Product Information

• Name: Dihydro Artemisinin Beta-D-Glucuronide (Mixture of Isomers)
• Synonyms: (3R,5aS,6R,8aS,9S,12R,12aS)-Decahydro-3,6,9-trimethyl- 3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl β-D-Glucopyranosiduronic Acid, Dihydroartemisinin Glucuronide, (3R,5aS,6R,8aS,9S,12R,12aS)-Decahydro-3,6,9-trimethyl- 3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl b-D-Glucopyranosiduronic Acid, Dihydro Artemisinin b-D-Glucuronide (Mixture of Isomers), (3R,5aS,6R,8aS,9S,12R,12aS)-Decahydro-3,6,9-trimethyl- 3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl -D-Glucopyranosiduronic Acid, Dihydro Artemisinin -D-Glucuronide (Mixture of Isomers)

Description

Applications A metabolite of Dihydro Artemisinin. Antimalarial.
References Madden, S., et al.: Drug Metab. Dispos., 24, 469 (1996), de Vries, P., et al.: Drugs, 52, 818 (1996), Smith, S., et al.: Biochem. Pharmacol., 53, 5 (1997),

• Brand: TRC

Chemical properties

• Molecular weight: 460.47
• Formula: C₂₁H₃₂O₁₁
• Color/Form: Neat
• InChI: InChI=1S/C21H32O11/c1-8-4-5-11-9(2)17(28-18-14(24)12(22)13(23)15(27-18)16(25)26)29-19-21(11)10(8)6-7-20(3,30-19)31-32-21/h8-15,17-19,22-24H,4-7H2,1-3H3,(H,25,26)/t8-,9-,10+,11+,12+,13+,14-,15+,17?,18?,19-,20-,21-/m1/s1
• InChI key: InChIKey=ZPXMEOGHWWIMAF-PYDHBSTJSA-N
• SMILES: C[C@@H]1CC[C@H]2[C@@H](C)C(O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4