1,2-Dihydro Fluticasone Propionate

CAS: 105613-90-9

Ref. TR-D449635

Product Information

• Name: 1,2-Dihydro Fluticasone Propionate
• Synonyms: Androst-4-ene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, S-(fluoromethyl) ester, (6a,11ß,16a,17a)-, Fluticasone Propionate Imp. E (EP), GR 51610X, unidentified impurity with RRT 1.23, disulphide dipropionate dithioketone (GR 247095X), dithio (GR 269949X), 6,9-Difluoro-11-Hydroxy-16-Methyl-3-Oxo-17-

Description

Impurity Fluticasone EP Impurity E
Stability Hygroscopic
Applications 1,2-Dihydro Fluticasone Propionate is an impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory.
References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009), Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al.: Gut, 32, 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 502.59
• Formula: C₂₅H₃₃F₃O₅S
• Color/Form: Neat
• InChI: InChI=1S/C25H33F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h9,13,15-16,18-19,30H,5-8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1