Dihydro-ergotoxine Methanesulfonate

CAS: 8067-24-1

Ref. TR-D450015

Product Information

• Name: Dihydro-ergotoxine Methanesulfonate
• Synonyms: Hydergine, 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotoxine deriv., Indolo[4,3-fg]quinoline, ergotoxine deriv., CCK 179, Circanol, Co-dercrine mesylate, Co-dergocrine mesylate, Codergine mesylate, Codergocrine methanesulfonate, Coristin, Dacoren, Deapril ST, Decril, Dihydroergotoxin mesylate, Dihydroergotoxin methanesulfonate, Dihydroergotoxine mesylate, Dihydroergotoxine methanesulfonate, Dulcion, Ergodesit, Ergohydrin, Ergoloid mesylates, Ergoplus, Hydergin, Hydergyne, Ischelium, Novofluen, Orphol, Perenan, Progeril, Redergin, Sponsin, Trigot,Dihydro-ergotoxine Monomethanesulfonate, (5'Alpha,10Alpha)-12'-Hydroxy-3',6',18-Trioxo-2',5'-Di(Propan-2-Yl)-9,10-Dihydroergotaman Methanesulfonate (1:1), 12'-Hydroxy-5'-(2-Methylbutan-2-Yl)-3',6',18-Trioxo-2'-(Propan-2-Yl)-9,10-Dihydroergotaman, 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotoxine deriv., Alkergot, Cck 179, Deapril, Dihydroergotoxine Mesilate, Dihydroergotoxine Monomethanesulphonate, Ergoloid Mesylate, Ergotoxine, dihydro-, methanesulfonate (1:1), Ergotoxine, dihydro-, monomethanesulfonate (salt), Gerimal, Indolo[4,3-fg]quinoline, ergotoxine deriv., Trigot

Description

Applications Dihydro-ergotoxine Methanesulfonate has been used to treat dementia and age-related cognitive impairment (such as in Alzheimer disease).
References Flynn, B., et al.: Ann. Pharmacother., 33, 188 (1999); Burian, E.: J. Am. Geriatr. Soc., 22, 126 (1974)

• Brand: TRC

Chemical properties

• Molecular weight: 659.79(R=CH(CH3)2), 707.84(R=CH2Ph), 685.83(R=CH2CH(CH3)2, or CH(CH3)CH2CH3)
• Formula: C₃₂H₄₅N₅O₈S(RCH(CH₃)₂C₃₆H₄₅N₅O₈S(RCH₂Ph)CH₄₇N₅O₈S(RCH₂CH(CH₃)₂orCH(CH₃)CH₂CH₃)
• Color/Form: Neat
• InChI: InChI=1S/C31H41N5O5.CH4O3S/c1-16(2)26-28(38)35-11-7-10-24(35)31(40)36(26)29(39)30(41-31,17(3)4)33-27(37)19-12-21-20-8-6-9-22-25(20)18(14-32-22)13-23(21)34(5)15-19;1-5(2,3)4/h6,8-9,14,16-17,19,21,23-24,26,32,40H,7,10-13,15H2,1-5H3,(H,33,37);1H3,(H,2,3,4)/t19-,21?,23-,24-,26-,30+,31-;/m1./s1