(3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester

CAS: 944115-20-2

Ref. TR-D450660

Product Information

• Name: (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester
• Synonyms: (5R)-5-(Ethoxycarbonyl)-5,6-dihydro-2H-1,4-thiazine-3-carboxylic Acid, Lanthionine Ketimine-R-5-ethyl Ester

Description

Applications (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester is the ethyl ester of Lanthionine Ketimine which is a natural sulfur amino acid metabolite. (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester is a cell-permeable synthetic derivative that promotes neurogenesis and reduces neurotoxicity of microglia-conditioned medium and has been tested as a treatment for multiple sclerosis in mice with promising findings.
References Dupree, J., et al.: J Neurochem., 134, 302 (2015);

• Brand: TRC

Chemical properties

• Molecular weight: 217.24
• Formula: C₈H₁₁NO₄S
• Color/Form: Neat
• InChI: InChI=1S/C8H11NO4S/c1-2-13-8(12)6-4-14-3-5(9-6)7(10)11/h3,6,9H,2,4H2,1H3,(H,10,11)/t6-/m1/s1
• InChI key: InChIKey=YRCLNQNKJMQRLB-ZCFIWIBFSA-N
• SMILES: CCOC(=O)[C@H]1CSC=C(C(=O)O)N1