(3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester-d5

CAS: 944115-20-2

Ref. TR-D450662

Product Information

• Name: (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester-d5
• Synonyms: (3R)-3-(1,1,2,2,2-pentadeuterioethoxycarbonyl)-3,6-dihydro-2H-1,4-thiazine-5-carboxylic acid

Description

Applications (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester-d5 is the labelled analogue of (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester which is the ethyl ester of Lanthionine Ketimine which is a natural sulfur amino acid metabolite. (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester is a cell-permeable synthetic derivative that promotes neurogenesis and reduces neurotoxicity of microglia-conditioned medium and has been tested as a treatment for multiple sclerosis in mice with promising findings.
References Dupree, J., et al.: J Neurochem., 134, 302 (2015);

• Brand: TRC

Chemical properties

• Molecular weight: 222.273
• Formula: C₈D₅H₆NO₄S
• Color/Form: Neat
• InChI: InChI=1S/C8H11NO4S/c1-2-13-8(12)6-4-14-3-5(9-6)7(10)11/h6H,2-4H2,1H3,(H,10,11)/t6-/m0/s1/i1D3,2D2
• InChI key: InChIKey=GEJLHOZZJNCUJX-PLFILOGFSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])OC(=O)[C@@H]1CSCC(C(=O)O)=N1