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N-[(7S)-6,7-Dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]-carbamic Acid (1R…
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N-[(7S)-6,7-Dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]-carbamic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester

CAS: 1197209-32-7

Ref. TR-D450790

5mg
Discontinued
10mg
Discontinued
2500µg
Discontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at .


Product Information

Name:
N-[(7S)-6,7-Dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]-carbamic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester
Description:

Applications N-[(7S)-6,7-Dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]-carbamic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester is an intermediate in the synthesis of (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one, a building block for γ-secretase inhibitors for treatment of Alzheimer's disease. Several γ-secretase inhibitors have been described that contain this compound.
References Beher, D., et al.: Exp. Opin. Investig. Drugs, 14, 1385 (2005), Fauq, A., et al.: Bioorg. Med. Chem. Lett., 17, 6392 (2007),

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
526.67
Formula:
C33H38N2O4
Color/Form:
White Solid
InChI:
InChI=1S/C33H38N2O4/c1-21(2)25-18-13-22(3)19-30(25)39-33(37)34-31-28-11-6-5-9-26(28)27-10-7-8-12-29(27)35(32(31)36)20-23-14-16-24(38-4)17-15-23/h5-12,14-17,21-22,25,30-31H,13,18-20H2,1-4H3,(H,34,37)/t22-,25+,30-,31+/m1/s1
InChI key:
InChIKey=JWBOIMRXGHLCPP-UHFFFAOYSA-N
SMILES:
Clc1ccc(C(c2ccccc2Cl)C(Cl)Cl)cc1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Inquiry about discontinued product: TR-D450790 N-[(7S)-6,7-Dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]-carbamic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester

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