6,7-Dihydro Rosuvastatin Sodium Salt

CAS: 1347362-67-7

Ref. TR-D452795

Product Information

• Name: 6,7-Dihydro Rosuvastatin Sodium Salt
• Synonyms: 5-Pyrimidineheptanoic acid, 4-(4-fluorophenyl)-ß,d-dihydroxy-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-, sodium salt (1:1), (ßR,dR)-, (ßR,dR)-4-(4-Fluorophenyl)-ß,d-dihydroxy-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidineheptanoic acid sodium salt (1:1), (3R,5R)-7-[4-(4-Fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyheptanoic acid sodium salt, 6,7-Dihydrorosuvastatin sodium

Description

Applications 6,7-Dihydro Rosuvastatin Sodium Salt is a derivative compound of (3R,5R)-Rosuvastatin Sodium salt (R700510). (3R,5R)-Rosuvastatin Sodium a diastereomer of Rosuvastatin (R700500) salt is used for treatment, prevention and combination therapy of lipid-related disorders. Rosuvastatin Calcium Salt is a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 505.54
• Formula: C₂₂H₂₉FN₃O₆S·Na
• Color/Form: Neat
• InChI: InChI=1S/C22H30FN3O6S.Na/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h5-8,13,16-17,27-28H,9-12H2,1-4H3,(H,29,30);/q;+1/p-1/t16-,17-;/m1./s1
• InChI key: InChIKey=IYNWBPFVIZBGIK-GBNZRNLASA-M
• SMILES: CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1CC[C@@H](O)C[C@@H](O)CC(=O)O[Na]