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Product Information
Name:
4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane
Controlled Product
Synonyms:
- 1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine
- 3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine
- (3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine
- 1-[3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl]methanamine
- 3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-methanamine
- C-(3,4-Dimethoxy-Bicyclo[4.2.0]Octa-1(6),2,4-Trien-7-Yl)-Methylamine
- [3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl]methanamine
- Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine, 3,4-dimethoxy-
Description:
Applications 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane is used in the synthesis of ent-Ivabradine Hydrochloride (I940505), which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also an antianginal.
References Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994); Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998); Borer, J.S., et al.: Circulation, 107, 817 (2003); DiFrancesco, D., et al.: Drugs, 64, 1757 (2004)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
193.24
Formula:
C11H15NO2
Color/Form:
Neat
InChI:
InChI=1S/C11H15NO2/c1-13-10-4-7-3-8(6-12)9(7)5-11(10)14-2/h4-5,8H,3,6,12H2,1-2H3
InChI key:
InChIKey=JDZSBHBIJDIACW-UHFFFAOYSA-N
SMILES:
COc1cc2c(cc1OC)C(CN)C2
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-D461855 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane
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