17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride
CAS: 467214-21-7
Ref. TR-D470930
| 25mg | 1,535.00 € | ||
| 2500µg | 227.00 € |
Estimated delivery in United States, on Thursday 16 Jan 2025
Product Information
Name:
17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride
Synonyms:
- 17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin Hydrochloride
- 17-N-(2-Dimethylaminoethylamino)-17-demethoxygeldanamycin Hydrochloride
- 17-[2-(Dimethylamino)ethylamino]-17-desmethylgeldanamycin Hydrochloride
- Alvespimycin Hydrochloride
- DMAG Hydrochloride
- NSC 707545 Hydrochloride
- 17-DMAG Hydrochloride
- 17-[2-(Dimethylamino)ethylamino]-17-desmethylgeldanamycin
- 17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin
- 17-Dmag
- See more synonyms
Description:
Applications 17-DMAG is an analogue of Gelamycin (G304500) and 17-(Allylamino)geldanamycin (A549650). 17-DMAG acts as a Hsp90 inhibitor and displays more potent antitumor activity than 17-AAG.
References Dote, H. et al.: Cancer Res., 66, 9211 (2006); Smith, V. et al.: Cancer Chemother. Pharmacol., 56, 126 (2005); Egorin, M.J. et al.: Cancer Chemother. Pharmacol., 49, 7 (2002);
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
653.21
Formula:
C32H49ClN4O8
Color/Form:
Neat
InChI:
InChI=1S/C32H48N4O8.ClH/c1-18-14-22-27(34-12-13-36(5)6)24(37)17-23(29(22)39)35-31(40)19(2)10-9-11-25(42-7)30(44-32(33)41)21(4)16-20(3)28(38)26(15-18)43-8;/h9-11,16-18,20,25-26,28,30,34,38H,12-15H2,1-8H3,(H2,33,41)(H,35,40);1H/b11-9-,19-10-,21-16-;/t18-,20+,25+,26+,28-,30+;/m1./s1
InChI key:
InChIKey=DFSYBWLNYPEFJK-VHYOVEFHSA-N
SMILES:
CO[C@H]1C=CC=C(C)C(=O)NC2=CC(=O)C(NCCN(C)C)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)C=C(C)[C@@H]1OC(N)=O)C2=O.Cl
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Technical inquiry about: TR-D470930 17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride
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